Managing your anemia with Aranesp®
along with your healthcare provider

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IMPORTANT SAFETY INFORMATION

Using Aranesp® (darbepoetin alfa) can lead to death or other serious side effects.

For patients with cancer:

Your healthcare provider has received special training through the ESA APPRISE Oncology Program in order to prescribe Aranesp®. Before you can begin to receive Aranesp®, you must sign the patient-healthcare provider acknowledgment form. When you sign this form, you are stating that your healthcare provider talked with you about the risks of taking Aranesp®.

These risks include that your tumor may grow faster and you may die sooner if you choose to take Aranesp®.

For all patients who take Aranesp®, including patients with cancer or chronic kidney disease:

You should not take Aranesp® if you:

Aranesp® may cause other serious side effects:

Tell your healthcare provider if you are pregnant or breastfeeding, or are planning to become pregnant or breastfeed.

If you know you are allergic to latex, talk to your healthcare provider before using Aranesp® because the needle cover on the prefilled syringe contains latex.

Common side effects of Aranesp® include:

These are not all of the possible side effects of Aranesp®. Tell your healthcare provider about any side effects that bother you or do not go away.

You are encouraged to report negative side effects of prescription drugs to the US Food and Drug Administration (FDA). Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

What you should know about Aranesp®

Aranesp® (darbepoetin alfa) is used to treat a lower than normal number of red blood cells (anemia) caused by chemotherapy that will be used for at least two months after starting Aranesp®.

Aranesp® is used to treat a lower than normal number of red blood cells (anemia) caused by chronic kidney disease in patients on dialysis and not on dialysis.

Aranesp® should not be used for the treatment of anemia:

Aranesp® has not been proven to improve quality of life, fatigue, or well-being.

Please see Full Prescribing Information, including Boxed WARNINGS, and Medication Guide.

Healthcare provider includes your doctor, nurse practitioner, nurse, and physician's assistant.